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Welcome to the Empowered Patient Podcast with Karen Jagoda.  This show is a window into the latest innovations in digital health and the changing dynamic between doctors and patients.

Topics on the show include

  • the emergence of precision medicine and breakthroughs in genomics
  • advances in biopharmaceuticals
  • age-related diseases and aging in place
  • using big data from wearables and sensors
  • transparency in the medical marketplace
  • challenges for connected health entrepreneurs

The audience includes researchers, medical professionals, patient advocates, entrepreneurs, patients, caregivers, solution providers, students, journalists, and investors.

May 10, 2022

Dr. Sameer Berry is the Chief Medical Officer of Oshi Health, and he shines a light on the challenges patients face from gastrointestinal conditions and the lack of effective treatments available from doctors for GI-related symptoms. While the reimbursement and payment model discourages a team approach to treating these patients, Oshi Health is taking a multidisciplinary integrated healthcare approach with a focus on the enteric nervous system. 

Sameer explains, "Where this comes from is the understanding that anatomically, there's actually an entirely separate nervous system that exists in the GI tract, and it's called the enteric nervous system. So, these are nerve cells, the same types of nerve cells that are in your spinal cord, in your brain, those nerve cells are in your gut. And just like the nerves in your brain respond to environmental stressors that might cause you to feel anxious, depressed, sad, happy, these nerves that are in your gut can respond to environmental stressors. But instead of causing you to feel anxious or depressed, they can cause GI symptoms."

"I don't see the use of drugs diminishing. I see us refining the molecular targets for the future of pharmacology and functional GI conditions. Where those drugs target, I think, will start to incorporate our understanding of the enteric nervous system and the interplay of the enteric nervous system with both the parasympathetic and the sympathetic nervous system."

@OshiHealth #GITwitter #MedTwitter #GI #IBS #GutHealth #MindGut #EntericNervousSystem

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