Aug 15, 2022
Rajatesh Gudibande is the Co-Founder and President of GraphWear Technologies, which has taken lessons from earlier self-monitoring blood glucose device development to come up with a patient-friendly system for continuous monitoring of glucose in people with diabetes. Using a needle-free device, this smart device is attached on the wrist, on the lower abdomen, or on the side arm.
Raj explains, "The principle of operation is fairly simple and also unique, in a way. Let's look at what is our source first. Skin is the largest organ in the human body, and it has access to interstitial fluid, which is the fluid just underneath the skin and a few layers off it, so underneath the stratum corneum. And so, if we are able to somehow put a device that can taste molecules by pulling them out a little bit just on the surface of the skin, then we can access whatever's there in the blood."
"But that requires a device that's very sensitive. So the first key principle operation is we have a sensitive material that is electronically active. It is specific to the molecules we are targeting, and then it converts the molecular information into electric signals and then transmits via Bluetooth to your phone. Think about it, it's literally an electronic tongue tasting molecules like glucose that come out. The key is the sensor sits on the surface of the skin, so there's no breaking of the skin whatsoever. Still, then there's a peripheral device that converts, stores, computes, and has the battery in it, and that then is a housing for which the device operates together as a system."
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